Anthelmintics

Anthelmintics – From Discovery to Resistance

The scientific meeting entitled 'Anthelmintics: From Discovery to Resistance' was held in San Francisco in February 2014. The themes of the meeting were drug discovery, modes of action and resistance. Both human and veterinary parasites were covered in the oral and poster presentations. The attendees were from both academic and industrial backgrounds. In the present article we introduce a numbe...

Anthelmintics Resistance; How to Overcome it?

Many parasitic helminthes of veterinary importance have genetic features that favor development of anthelmintic resistance, this becoming a major worldwide constrain in livestock production. The development of anthelmintic resistance poses a large threat to future production and welfare of grazing animals. Development of variable degrees of resistance among different species of gastrointestinal...

Anthelmintics for Dictyocaulus filaria in Sheep

Parasite surveillance and novel use of anthelmintics in cattle

Background Cattle are economically the most important livestock for farmers in Sweden. However, both dairy and beef production has been subjected to considerable structural change over recent decades. Currently, there are approximately 1.5 million cattle, including ≈370 000 dairy cows producing milk worth 1 m€ [1]. The trend is that the numbers of dairy cows are decreasing slowly, while beef co...

[Determination of benzimidazole anthelmintics in livestock foods by HPLC].

A simple and rapid liquid chromatographic method was developed for the simultaneous determination of twelve benzimidazole anthelmintics in livestock foods using reversed-phase high-performance liquid chromatography with photodiode array detection (PDA). A sample was homogenized with acetonitrile and n-hexane, and centrifuged. The acetonitrile phase was isolated and evaporated. The residue was d...